Fly Lab

 

Research on male reproductive ageing is lagging behind research on females but is nevertheless important. We use evolutionary, comparative and molecular approaches to understand how advancing male age effects ejaculate traits, the biological and environmental factors that mediate this effect and the fitness consequences of advancing age for the male itself, its female mate and its offspring. This is important both for understanding how different components of the ejaculate respond to ageing and decipher how each component impacts reproductive success and the fitness of the offspring. We aim to use this knowledge to explore interventions that could delay male reproductive ageing and mitigate the potentially detrimental impacts of paternal age on offspring. We use the tractable model organism Drosophila melanogaster the fruit fly in our research.

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PI

Irem Sepil

Dr Irem Sepil

Group members

tempimagef52qtg maria filippou

Maria Filippou

img 1557 elsa heywood

Elsa Heywood

img 0961 selah makinishi

Selah Makinishi

20260925 171656 eleanor mckelvey

Eleanor

krish sanghvi

Dr Krish Sanghvi

Devi Satarkar

Devi Satarkar

Irem Sepil

Dr Irem Sepil

andrew spires

Andrew Spires